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Using excess deaths and testing statistics to improve estimates of COVID-19 mortalities

Factors such as non-uniform definitions of mortality, uncertainty in disease prevalence, and biased sampling complicate the quantification of fatality during an epidemic. Regardless of the employed fatality measure, the infected population and the number of infection-caused deaths need to be consist...

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Autores principales: Böttcher, Lucas, D’Orsogna, Maria R., Chou, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7814852/
https://www.ncbi.nlm.nih.gov/pubmed/33469606
http://dx.doi.org/10.1101/2021.01.10.21249524
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author Böttcher, Lucas
D’Orsogna, Maria R.
Chou, Tom
author_facet Böttcher, Lucas
D’Orsogna, Maria R.
Chou, Tom
author_sort Böttcher, Lucas
collection PubMed
description Factors such as non-uniform definitions of mortality, uncertainty in disease prevalence, and biased sampling complicate the quantification of fatality during an epidemic. Regardless of the employed fatality measure, the infected population and the number of infection-caused deaths need to be consistently estimated for comparing mortality across regions. We combine historical and current mortality data, a statistical testing model, and an SIR epidemic model, to improve estimation of mortality. We find that the average excess death across the entire US is 13% higher than the number of reported COVID-19 deaths. In some areas, such as New York City, the number of weekly deaths is about eight times higher than in previous years. Other countries such as Peru, Ecuador, Mexico, and Spain exhibit excess deaths significantly higher than their reported COVID-19 deaths. Conversely, we find negligible or negative excess deaths for part and all of 2020 for Denmark, Germany, and Norway.
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spelling pubmed-78148522021-01-20 Using excess deaths and testing statistics to improve estimates of COVID-19 mortalities Böttcher, Lucas D’Orsogna, Maria R. Chou, Tom medRxiv Article Factors such as non-uniform definitions of mortality, uncertainty in disease prevalence, and biased sampling complicate the quantification of fatality during an epidemic. Regardless of the employed fatality measure, the infected population and the number of infection-caused deaths need to be consistently estimated for comparing mortality across regions. We combine historical and current mortality data, a statistical testing model, and an SIR epidemic model, to improve estimation of mortality. We find that the average excess death across the entire US is 13% higher than the number of reported COVID-19 deaths. In some areas, such as New York City, the number of weekly deaths is about eight times higher than in previous years. Other countries such as Peru, Ecuador, Mexico, and Spain exhibit excess deaths significantly higher than their reported COVID-19 deaths. Conversely, we find negligible or negative excess deaths for part and all of 2020 for Denmark, Germany, and Norway. Cold Spring Harbor Laboratory 2021-01-12 /pmc/articles/PMC7814852/ /pubmed/33469606 http://dx.doi.org/10.1101/2021.01.10.21249524 Text en https://creativecommons.org/licenses/by/4.0/This work is licensed under a Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/) , which allows reusers to distribute, remix, adapt, and build upon the material in any medium or format, so long as attribution is given to the creator. The license allows for commercial use.
spellingShingle Article
Böttcher, Lucas
D’Orsogna, Maria R.
Chou, Tom
Using excess deaths and testing statistics to improve estimates of COVID-19 mortalities
title Using excess deaths and testing statistics to improve estimates of COVID-19 mortalities
title_full Using excess deaths and testing statistics to improve estimates of COVID-19 mortalities
title_fullStr Using excess deaths and testing statistics to improve estimates of COVID-19 mortalities
title_full_unstemmed Using excess deaths and testing statistics to improve estimates of COVID-19 mortalities
title_short Using excess deaths and testing statistics to improve estimates of COVID-19 mortalities
title_sort using excess deaths and testing statistics to improve estimates of covid-19 mortalities
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7814852/
https://www.ncbi.nlm.nih.gov/pubmed/33469606
http://dx.doi.org/10.1101/2021.01.10.21249524
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