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Selectivity over coverage in de novo sequencing of IgGs

Although incredibly diverse in specificity, millions of unique Immunoglobulin G (IgG) molecules in the human antibody repertoire share most of their amino acid sequence. These constant parts of IgG do not yield any useful information in attempts to sequence antibodies de novo. Therefore, methods foc...

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Detalles Bibliográficos
Autores principales: den Boer, Maurits A., Greisch, Jean-Francois, Tamara, Sem, Bondt, Albert, Heck, Albert J. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7814886/
https://www.ncbi.nlm.nih.gov/pubmed/33520151
http://dx.doi.org/10.1039/d0sc03438j

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