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NODAL inhibition promotes differentiation of pacemaker-like cardiomyocytes from human induced pluripotent stem cells

Directed cardiomyogenesis from human induced pluripotent stem cells (hiPSCs) has been greatly improved in the last decade but directed differentiation to pacemaking cardiomyocytes (CMs) remains incompletely understood. In this study, we demonstrated that inhibition of NODAL signaling by a specific N...

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Detalles Bibliográficos
Autores principales: Yechikov, Sergey, Kao, Hillary K.J., Chang, Che-Wei, Pretto, Dalyir, Zhang, Xiao-Dong, Sun, Yao-Hui, Smithers, Regan, Sirish, Padmini, Nolta, Jan A., Chan, James W., Chiamvimonvat, Nipavan, Lieu, Deborah K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7814970/
https://www.ncbi.nlm.nih.gov/pubmed/33128951
http://dx.doi.org/10.1016/j.scr.2020.102043