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Longitudinal FEV(1) and Exacerbation Risk in COPD: Quantifying the Association Using Joint Modelling
BACKGROUND: Lung function, measured as forced expiratory volume in one second (FEV(1)), and exacerbations are two endpoints evaluated in chronic obstructive pulmonary disease (COPD) clinical trials. Joint analysis of these endpoints could potentially increase statistical power and enable assessment...
Autores principales: | Zhudenkov, Kirill, Palmér, Robert, Jauhiainen, Alexandra, Helmlinger, Gabriel, Stepanov, Oleg, Peskov, Kirill, Eriksson, Ulf G, Wählby Hamrén, Ulrika |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815071/ https://www.ncbi.nlm.nih.gov/pubmed/33488073 http://dx.doi.org/10.2147/COPD.S284720 |
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