Cargando…
Effect of tocilizumab on clinical outcomes at 15 days in patients with severe or critical coronavirus disease 2019: randomised controlled trial
OBJECTIVE: To determine whether tocilizumab improves clinical outcomes for patients with severe or critical coronavirus disease 2019 (covid-19). DESIGN: Randomised, open label trial. SETTING: Nine hospitals in Brazil, 8 May to 17 July 2020. PARTICIPANTS: Adults with confirmed covid-19 who were recei...
Autores principales: | Veiga, Viviane C, Prats, João A G G, Farias, Danielle L C, Rosa, Regis G, Dourado, Leticia K, Zampieri, Fernando G, Machado, Flávia R, Lopes, Renato D, Berwanger, Otavio, Azevedo, Luciano C P, Avezum, Álvaro, Lisboa, Thiago C, Rojas, Salomón S O, Coelho, Juliana C, Leite, Rodrigo T, Carvalho, Júlio C, Andrade, Luis E C, Sandes, Alex F, Pintão, Maria C T, Castro, Claudio G, Santos, Sueli V, de Almeida, Thiago M L, Costa, André N, Gebara, Otávio C E, de Freitas, Flávio G Rezende, Pacheco, Eduardo S, Machado, David J B, Martin, Josiane, Conceição, Fábio G, Siqueira, Suellen R R, Damiani, Lucas P, Ishihara, Luciana M, Schneider, Daniel, de Souza, Denise, Cavalcanti, Alexandre B, Scheinberg, Phillip |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group Ltd.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815251/ https://www.ncbi.nlm.nih.gov/pubmed/33472855 http://dx.doi.org/10.1136/bmj.n84 |
Ejemplares similares
-
Rationale and design of the “Tocilizumab in patients with moderate to severe COVID-19: an open-label multicentre randomized controlled” trial (TOCIBRAS)
por: de Farias, Danielle Leão Cordeiro, et al.
Publicado: (2020) -
Hydroxychloroquine with or without Azithromycin in Mild-to-Moderate Covid-19
por: Cavalcanti, Alexandre B., et al.
Publicado: (2020) -
Azithromycin in addition to standard of care versus standard of care alone in the treatment of patients admitted to the hospital with severe COVID-19 in Brazil (COALITION II): a randomised clinical trial
por: Furtado, Remo H M, et al.
Publicado: (2020) -
Justificativa e Desenho do Ensaio Clínico Randomizado COVID-19 Outpatient Prevention Evaluation (COPE - Coalition V): Hidroxicloroquina vs. Placebo em Pacientes Não Hospitalizados
por: de Oliveira, Haliton Alves, et al.
Publicado: (2022) -
Antivirals for adult patients hospitalised with SARS-CoV-2 infection: a randomised, phase II/III, multicentre, placebo-controlled, adaptive study, with multiple arms and stages. COALITION COVID-19 BRAZIL IX – REVOLUTIOn trial
por: Maia, Israel S., et al.
Publicado: (2023)