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How selecting best upfront therapy for metastatic disease?—Focus on ROS1-rearranged disease

ROS proto-oncogene 1 (ROS1) rearrangements defines a distinct group of non-small cell lung cancer (NSCLC), mainly represented by younger subjects, never smokers and with adenocarcinoma histology. Fusions involving ROS1 gene are present in 1-2% of lung adenocarcinomas and other solid tumors. Identifi...

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Detalles Bibliográficos
Autores principales: Landi, Lorenza, Cappuzzo, Federico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815342/
https://www.ncbi.nlm.nih.gov/pubmed/33489827
http://dx.doi.org/10.21037/tlcr-20-1109