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The Role of Acupuncture Improving Cognitive Deficits due to Alzheimer's Disease or Vascular Diseases through Regulating Neuroplasticity

Dementia affects millions of elderly worldwide causing remarkable costs to society, but effective treatment is still lacking. Acupuncture is one of the complementary therapies that has been applied to cognitive deficits such as Alzheimer's disease (AD) and vascular cognitive impairment (VCI), w...

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Autores principales: Ji, Shaozhen, Duan, Jiayu, Hou, Xiaobing, Zhou, Li, Qin, Weilan, Niu, Huanmin, Luo, Shuyun, Zhang, Yunling, Chan, Piu, Jin, Xianglan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815402/
https://www.ncbi.nlm.nih.gov/pubmed/33505460
http://dx.doi.org/10.1155/2021/8868447
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author Ji, Shaozhen
Duan, Jiayu
Hou, Xiaobing
Zhou, Li
Qin, Weilan
Niu, Huanmin
Luo, Shuyun
Zhang, Yunling
Chan, Piu
Jin, Xianglan
author_facet Ji, Shaozhen
Duan, Jiayu
Hou, Xiaobing
Zhou, Li
Qin, Weilan
Niu, Huanmin
Luo, Shuyun
Zhang, Yunling
Chan, Piu
Jin, Xianglan
author_sort Ji, Shaozhen
collection PubMed
description Dementia affects millions of elderly worldwide causing remarkable costs to society, but effective treatment is still lacking. Acupuncture is one of the complementary therapies that has been applied to cognitive deficits such as Alzheimer's disease (AD) and vascular cognitive impairment (VCI), while the underlying mechanisms of its therapeutic efficiency remain elusive. Neuroplasticity is defined as the ability of the nervous system to adapt to internal and external environmental changes, which may support some data to clarify mechanisms how acupuncture improves cognitive impairments. This review summarizes the up-to-date and comprehensive information on the effectiveness of acupuncture treatment on neurogenesis and gliogenesis, synaptic plasticity, related regulatory factors, and signaling pathways, as well as brain network connectivity, to lay ground for fully elucidating the potential mechanism of acupuncture on the regulation of neuroplasticity and promoting its clinical application as a complementary therapy for AD and VCI.
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spelling pubmed-78154022021-01-26 The Role of Acupuncture Improving Cognitive Deficits due to Alzheimer's Disease or Vascular Diseases through Regulating Neuroplasticity Ji, Shaozhen Duan, Jiayu Hou, Xiaobing Zhou, Li Qin, Weilan Niu, Huanmin Luo, Shuyun Zhang, Yunling Chan, Piu Jin, Xianglan Neural Plast Review Article Dementia affects millions of elderly worldwide causing remarkable costs to society, but effective treatment is still lacking. Acupuncture is one of the complementary therapies that has been applied to cognitive deficits such as Alzheimer's disease (AD) and vascular cognitive impairment (VCI), while the underlying mechanisms of its therapeutic efficiency remain elusive. Neuroplasticity is defined as the ability of the nervous system to adapt to internal and external environmental changes, which may support some data to clarify mechanisms how acupuncture improves cognitive impairments. This review summarizes the up-to-date and comprehensive information on the effectiveness of acupuncture treatment on neurogenesis and gliogenesis, synaptic plasticity, related regulatory factors, and signaling pathways, as well as brain network connectivity, to lay ground for fully elucidating the potential mechanism of acupuncture on the regulation of neuroplasticity and promoting its clinical application as a complementary therapy for AD and VCI. Hindawi 2021-01-12 /pmc/articles/PMC7815402/ /pubmed/33505460 http://dx.doi.org/10.1155/2021/8868447 Text en Copyright © 2021 Shaozhen Ji et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Ji, Shaozhen
Duan, Jiayu
Hou, Xiaobing
Zhou, Li
Qin, Weilan
Niu, Huanmin
Luo, Shuyun
Zhang, Yunling
Chan, Piu
Jin, Xianglan
The Role of Acupuncture Improving Cognitive Deficits due to Alzheimer's Disease or Vascular Diseases through Regulating Neuroplasticity
title The Role of Acupuncture Improving Cognitive Deficits due to Alzheimer's Disease or Vascular Diseases through Regulating Neuroplasticity
title_full The Role of Acupuncture Improving Cognitive Deficits due to Alzheimer's Disease or Vascular Diseases through Regulating Neuroplasticity
title_fullStr The Role of Acupuncture Improving Cognitive Deficits due to Alzheimer's Disease or Vascular Diseases through Regulating Neuroplasticity
title_full_unstemmed The Role of Acupuncture Improving Cognitive Deficits due to Alzheimer's Disease or Vascular Diseases through Regulating Neuroplasticity
title_short The Role of Acupuncture Improving Cognitive Deficits due to Alzheimer's Disease or Vascular Diseases through Regulating Neuroplasticity
title_sort role of acupuncture improving cognitive deficits due to alzheimer's disease or vascular diseases through regulating neuroplasticity
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815402/
https://www.ncbi.nlm.nih.gov/pubmed/33505460
http://dx.doi.org/10.1155/2021/8868447
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