HDAC1-mediated deacetylation of HIF1α prevents atherosclerosis progression by promoting miR-224-3p-mediated inhibition of FOSL2

We intended to characterize functional relevance of microRNA (miR)-224-3p in endothelial cell (EC) apoptosis and reactive oxygen species (ROS) accumulation in atherosclerosis, considering also the integral involvement of histone deacetylase 1 (HDAC1)-mediated hypoxia-inducible factor-1α (HIF1α) deac...

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Detalles Bibliográficos
Autores principales: Wang, Hao, Sugimoto, Kazuo, Lu, Hao, Yang, Wan-Yong, Liu, Ji-Yue, Yang, Hong-Yu, Song, Yue-Bo, Yan, Dong, Zou, Tian-Yu, Shen, Si
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815465/
https://www.ncbi.nlm.nih.gov/pubmed/33510945
http://dx.doi.org/10.1016/j.omtn.2020.10.044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815465/
https://www.ncbi.nlm.nih.gov/pubmed/33510945
http://dx.doi.org/10.1016/j.omtn.2020.10.044

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