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Antibody-activated trans-endothelial delivery of mesoporous organosilica nanomedicine augments tumor extravasation and anti-cancer immunotherapy

Tumor vasculature constitutes a formidable hurdle for the efficient delivery of cancer nanomedicine into tumors. The leverage of passive pathway through inter-endothelial gaps in tumor blood vessels might account for limited extravasation of nanomedicine into tumor microenvironment (TME). Herein, An...

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Detalles Bibliográficos
Autores principales: Huang, Tinglei, Li, Shuang, Fang, Jianchen, Li, Fuli, Tu, Shuiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815474/
https://www.ncbi.nlm.nih.gov/pubmed/33511314
http://dx.doi.org/10.1016/j.bioactmat.2020.12.023