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Antibody-activated trans-endothelial delivery of mesoporous organosilica nanomedicine augments tumor extravasation and anti-cancer immunotherapy
Tumor vasculature constitutes a formidable hurdle for the efficient delivery of cancer nanomedicine into tumors. The leverage of passive pathway through inter-endothelial gaps in tumor blood vessels might account for limited extravasation of nanomedicine into tumor microenvironment (TME). Herein, An...
Autores principales: | Huang, Tinglei, Li, Shuang, Fang, Jianchen, Li, Fuli, Tu, Shuiping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
KeAi Publishing
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815474/ https://www.ncbi.nlm.nih.gov/pubmed/33511314 http://dx.doi.org/10.1016/j.bioactmat.2020.12.023 |
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