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Calcium Imaging and the Curse of Negativity

The imaging of neuronal activity using calcium indicators has become a staple of modern neuroscience. However, without ground truths, there is a real risk of missing a significant portion of the real responses. Here, we show that a common assumption, the non-negativity of the neuronal responses as d...

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Detalles Bibliográficos
Autores principales: Vanwalleghem, Gilles, Constantin, Lena, Scott, Ethan K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815594/
https://www.ncbi.nlm.nih.gov/pubmed/33488363
http://dx.doi.org/10.3389/fncir.2020.607391