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Scaffold-free human mesenchymal stem cell construct geometry regulates long bone regeneration

Biomimetic bone tissue engineering strategies partially recapitulate development. We recently showed functional restoration of femoral defects using scaffold-free human mesenchymal stem cell (hMSC) condensates featuring localized morphogen presentation with delayed in vivo mechanical loading. Possib...

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Detalles Bibliográficos
Autores principales:	Herberg, Samuel, Varghai, Daniel, Alt, Daniel S., Dang, Phuong N., Park, Honghyun, Cheng, Yuxuan, Shin, Jung-Youn, Dikina, Anna D., Boerckel, Joel D., Rolle, Marsha W., Alsberg, Eben
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815708/ https://www.ncbi.nlm.nih.gov/pubmed/33469154 http://dx.doi.org/10.1038/s42003-020-01576-y

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