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Integrated photothermal decontamination device for N95 respirators

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) responsible for the COVID-19 global pandemic has infected over 25 million people worldwide and resulted in the death of millions. The COVID-19 pandemic has also resulted in a shortage of personal protective equipment (PPE) in many regi...

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Autores principales: Muñoz, Marcelo, Comtois-Bona, Maxime, Cortes, David, Cimenci, Cagla Eren, Du, Qiujiang, Thompson, Collin, Figueroa, Juan David, Franklin, Vivian, Liu, Peter, Alarcon, Emilio I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815715/
https://www.ncbi.nlm.nih.gov/pubmed/33469049
http://dx.doi.org/10.1038/s41598-020-80908-8
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author Muñoz, Marcelo
Comtois-Bona, Maxime
Cortes, David
Cimenci, Cagla Eren
Du, Qiujiang
Thompson, Collin
Figueroa, Juan David
Franklin, Vivian
Liu, Peter
Alarcon, Emilio I.
author_facet Muñoz, Marcelo
Comtois-Bona, Maxime
Cortes, David
Cimenci, Cagla Eren
Du, Qiujiang
Thompson, Collin
Figueroa, Juan David
Franklin, Vivian
Liu, Peter
Alarcon, Emilio I.
author_sort Muñoz, Marcelo
collection PubMed
description The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) responsible for the COVID-19 global pandemic has infected over 25 million people worldwide and resulted in the death of millions. The COVID-19 pandemic has also resulted in a shortage of personal protective equipment (PPE) in many regions around the world, particularly in middle- and low-income countries. The shortages of PPE, such as N95 respirators, is something that will persist until an effective vaccine is made available. Thus, devices that while being easy to operate can also be rapidly deployed in health centers, and long-term residences without the need for major structural overhaul are instrumental to sustainably use N95 respirators. In this report, we present the design and validation of a decontamination device that combines UV-C & B irradiation with mild-temperature treatment. The device can decontaminate up to 20 masks in a cycle of < 30 min. The decontamination process did not damage or reduce the filtering capacity of the masks. Further, the efficacy of the device to eliminate microbes and viruses from the masks was also evaluated. The photothermal treatment of our device was capable of eradicating > 99.9999% of the bacteria and > 99.99% of the virus tested.
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spelling pubmed-78157152021-01-21 Integrated photothermal decontamination device for N95 respirators Muñoz, Marcelo Comtois-Bona, Maxime Cortes, David Cimenci, Cagla Eren Du, Qiujiang Thompson, Collin Figueroa, Juan David Franklin, Vivian Liu, Peter Alarcon, Emilio I. Sci Rep Article The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) responsible for the COVID-19 global pandemic has infected over 25 million people worldwide and resulted in the death of millions. The COVID-19 pandemic has also resulted in a shortage of personal protective equipment (PPE) in many regions around the world, particularly in middle- and low-income countries. The shortages of PPE, such as N95 respirators, is something that will persist until an effective vaccine is made available. Thus, devices that while being easy to operate can also be rapidly deployed in health centers, and long-term residences without the need for major structural overhaul are instrumental to sustainably use N95 respirators. In this report, we present the design and validation of a decontamination device that combines UV-C & B irradiation with mild-temperature treatment. The device can decontaminate up to 20 masks in a cycle of < 30 min. The decontamination process did not damage or reduce the filtering capacity of the masks. Further, the efficacy of the device to eliminate microbes and viruses from the masks was also evaluated. The photothermal treatment of our device was capable of eradicating > 99.9999% of the bacteria and > 99.99% of the virus tested. Nature Publishing Group UK 2021-01-19 /pmc/articles/PMC7815715/ /pubmed/33469049 http://dx.doi.org/10.1038/s41598-020-80908-8 Text en © The Author(s) 2021 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Muñoz, Marcelo
Comtois-Bona, Maxime
Cortes, David
Cimenci, Cagla Eren
Du, Qiujiang
Thompson, Collin
Figueroa, Juan David
Franklin, Vivian
Liu, Peter
Alarcon, Emilio I.
Integrated photothermal decontamination device for N95 respirators
title Integrated photothermal decontamination device for N95 respirators
title_full Integrated photothermal decontamination device for N95 respirators
title_fullStr Integrated photothermal decontamination device for N95 respirators
title_full_unstemmed Integrated photothermal decontamination device for N95 respirators
title_short Integrated photothermal decontamination device for N95 respirators
title_sort integrated photothermal decontamination device for n95 respirators
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815715/
https://www.ncbi.nlm.nih.gov/pubmed/33469049
http://dx.doi.org/10.1038/s41598-020-80908-8
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