Mechanistic basis of breast cancer resistance protein inhibition by new indeno[1,2-b]indoles

The ATP-binding cassette transporter ABCG2 mediates the efflux of several chemotherapeutic drugs, contributing to the development of multidrug resistance (MDR) in many cancers. The most promising strategy to overcome ABCG2-mediated MDR is the use of specific inhibitors. Despite many efforts, the ide...

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Detalles Bibliográficos
Autores principales: Kita, Diogo Henrique, Guragossian, Nathalie, Zattoni, Ingrid Fatima, Moure, Vivian Rotuno, Rego, Fabiane Gomes de Moraes, Lusvarghi, Sabrina, Moulenat, Thomas, Belhani, Billel, Picheth, Geraldo, Bouacida, Sofiane, Bouaziz, Zouhair, Marminon, Christelle, Berredjem, Malika, Jose, Joachim, Gonçalves, Marcos Brown, Ambudkar, Suresh V., Valdameri, Glaucio, Le Borgne, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815716/
https://www.ncbi.nlm.nih.gov/pubmed/33469044
http://dx.doi.org/10.1038/s41598-020-79892-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815716/
https://www.ncbi.nlm.nih.gov/pubmed/33469044
http://dx.doi.org/10.1038/s41598-020-79892-w

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