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PI3K/Akt pathway and Nanog maintain cancer stem cells in sarcomas

The self-renewal transcription factor Nanog and the phosphoinositide 3-kinase (PI3K)–Akt pathway are known to be essential for maintenance of mesenchymal stem cells. We evaluated their contribution to the maintenance of CD133(+) cancer stem-like cells (CSCs) and spheroid-forming cells in patient-der...

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Detalles Bibliográficos
Autores principales:	Yoon, Changhwan, Lu, Jun, Yi, Brendan C., Chang, Kevin K., Simon, M. Celeste, Ryeom, Sandra, Yoon, Sam S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815726/ https://www.ncbi.nlm.nih.gov/pubmed/33468992 http://dx.doi.org/10.1038/s41389-020-00300-z

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