AHA1 upregulates IDH1 and metabolic activity to promote growth and metastasis and predicts prognosis in osteosarcoma

Osteosarcoma (OS) is the most common primary malignant bone tumor in children and adolescents. Although activator of HSP90 ATPase activity 1 (AHA1) is reported to be a potential oncogene, its role in osteosarcoma progression remains largely unclear. Since metabolism reprogramming is involved in tumo...

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Detalles Bibliográficos
Autores principales: Zheng, Diwei, Liu, Weihai, Xie, Wenlin, Huang, Guanyu, Jiang, Qiwei, Yang, Yang, Huang, Jiarong, Xing, Zihao, Yuan, Mengling, Wei, Mengning, Li, Yao, Yin, Junqiang, Shen, Jingnan, Shi, Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815748/
https://www.ncbi.nlm.nih.gov/pubmed/33468990
http://dx.doi.org/10.1038/s41392-020-00387-1

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