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CD4+T cells in ageing-associated interstitial lung abnormalities show evidence of pro-inflammatory phenotypic and functional profile

BACKGROUND: Interstitial lung abnormalities (ILA) occur in around 10% of subjects over 60 years, and are associated with a higher rate of all-cause mortality. The pathogenic mechanisms are unclear, and the putative contribution of alterations in the immune response has not been explored. Normal agei...

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Detalles Bibliográficos
Autores principales: Machahua, Carlos, Buendia-Roldan, Ivette, Ocaña-Guzman, Ranferi, Molina-Molina, María, Pardo, Annie, Chavez-Galan, Leslie, Selman, Moises
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815886/
https://www.ncbi.nlm.nih.gov/pubmed/33298584
http://dx.doi.org/10.1136/thoraxjnl-2020-215520