Tumor infiltrating lymphocyte clusters are associated with response to immune checkpoint inhibition in BRAF V600(E/K) mutated malignant melanomas

Patients with metastasized malignant melanomas (MM) are regularly treated with immune checkpoint inhibitors (CPI). Within our study, we evaluated the predictive value of tumor infiltrating lymphocyte (TIL) clusters in primary MM and its association to molecular subtypes to predict response to CPI tr...

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Detalles Bibliográficos
Autores principales: Klein, Sebastian, Mauch, Cornelia, Brinker, Klaus, Noh, Ka-Won, Knez, Sonja, Büttner, Reinhard, Quaas, Alexander, Helbig, Doris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815914/
https://www.ncbi.nlm.nih.gov/pubmed/33469107
http://dx.doi.org/10.1038/s41598-021-81330-4

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