Genomic Safe Harbor Expression of PAX7 for the Generation of Engraftable Myogenic Progenitors

Inducible expression of PAX7 in differentiating pluripotent stem cells (PSCs) allows massively scalable generation of human myogenic progenitors, which upon transplantation into dystrophic muscles give rise to donor-derived myofibers and satellite cells. Therefore, PSC-derived PAX7(+) myogenic proge...

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Detalles Bibliográficos
Autores principales: Kim, Hyunkee, Selvaraj, Sridhar, Kiley, James, Azzag, Karim, Garay, Bayardo I., Perlingeiro, Rita C.R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815936/
https://www.ncbi.nlm.nih.gov/pubmed/33275879
http://dx.doi.org/10.1016/j.stemcr.2020.11.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815936/
https://www.ncbi.nlm.nih.gov/pubmed/33275879
http://dx.doi.org/10.1016/j.stemcr.2020.11.001

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