Apoptosis, G1 Phase Stall, and Premature Differentiation Account for Low Chimeric Competence of Human and Rhesus Monkey Naive Pluripotent Stem Cells

After reprogramming to naive pluripotency, human pluripotent stem cells (PSCs) still exhibit very low ability to make interspecies chimeras. Whether this is because they are inherently devoid of the attributes of chimeric competency or because naive PSCs cannot colonize embryos from distant species...

Descripción completa

Detalles Bibliográficos
Autores principales: Aksoy, Irène, Rognard, Cloé, Moulin, Anaïs, Marcy, Guillaume, Masfaraud, Etienne, Wianny, Florence, Cortay, Véronique, Bellemin-Ménard, Angèle, Doerflinger, Nathalie, Dirheimer, Manon, Mayère, Chloé, Bourillot, Pierre-Yves, Lynch, Cian, Raineteau, Olivier, Joly, Thierry, Dehay, Colette, Serrano, Manuel, Afanassieff, Marielle, Savatier, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7815945/
https://www.ncbi.nlm.nih.gov/pubmed/33382978
http://dx.doi.org/10.1016/j.stemcr.2020.12.004

Ejemplares similares

Ejemplares similares