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Characteristics and outcomes of Ludwig's angina in patients admitted to the intensive care unit: A 6-year retrospective study of 29 patients
BACKGROUND/PURPOSE: Ludwig's angina (LA) still presents regularly and various characteristics are documented, but patients admitted to the Intensive Care Unit (ICU) has not been studied. The purpose of this study was to investigate the clinical characteristics and outcomes of patients with LA w...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Association for Dental Sciences of the Republic of China
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7816034/ https://www.ncbi.nlm.nih.gov/pubmed/33505615 http://dx.doi.org/10.1016/j.jds.2019.10.004 |
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author | Lin, Qing-Ling Du, Hong-Liang Xiong, Huai-Yu Li, Bin Liu, Jian Xing, Xiao-Hua |
author_facet | Lin, Qing-Ling Du, Hong-Liang Xiong, Huai-Yu Li, Bin Liu, Jian Xing, Xiao-Hua |
author_sort | Lin, Qing-Ling |
collection | PubMed |
description | BACKGROUND/PURPOSE: Ludwig's angina (LA) still presents regularly and various characteristics are documented, but patients admitted to the Intensive Care Unit (ICU) has not been studied. The purpose of this study was to investigate the clinical characteristics and outcomes of patients with LA who were admitted to ICU. MATERIALS AND METHODS: We retrospectively reviewed all 29 patients with LA who were admitted to the ICU of a university hospital from January 2013 to October 2018. Results were evaluated via descriptive analysis. The Log–Rank test was used to analyze the hospital/ICU length of stay (LOS). RESULTS: The male: female ratio was 2.63:1. Mean age was 53.41 ± 16.57 years (range 8–78 years). Concomitant conditions comprised diabetes mellitus in 10 patients (34.48%), and hypertension in six (20.69%). The main reason for ICU admission was surgical (44.83%). The mean Acute Physiology, Age, Chronic Health Evaluation II (APACHE II) and the Sequential Organ Failure Assessment (SOFA) scores were 13.52 ± 3.18 and 3.83 ± 2.89, respectively. Twenty-eight patients (96.55%) received respiratory support. Sixteen patients (55.17%) had positive bacterial culture results. Fourteen bacterial strains were detected, most of which were gram-positive (72.72%). Mean LOS was 6.89 ± 14.39 days (range 0.5–73 days), and 24.79 ± 16 days in the hospital. The ICU mortality rate was 10.34%. Compared with LA patients without descending necrotizing mediastinitis (DNM), those with DNM had longer ICU and hospital LOS. The laboratory investigations were higher. CONCLUSION: LA patients in ICU were predominantly male, with a wide range age, high incidence of complications, long hospital LOS. |
format | Online Article Text |
id | pubmed-7816034 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Association for Dental Sciences of the Republic of China |
record_format | MEDLINE/PubMed |
spelling | pubmed-78160342021-01-26 Characteristics and outcomes of Ludwig's angina in patients admitted to the intensive care unit: A 6-year retrospective study of 29 patients Lin, Qing-Ling Du, Hong-Liang Xiong, Huai-Yu Li, Bin Liu, Jian Xing, Xiao-Hua J Dent Sci Original Article BACKGROUND/PURPOSE: Ludwig's angina (LA) still presents regularly and various characteristics are documented, but patients admitted to the Intensive Care Unit (ICU) has not been studied. The purpose of this study was to investigate the clinical characteristics and outcomes of patients with LA who were admitted to ICU. MATERIALS AND METHODS: We retrospectively reviewed all 29 patients with LA who were admitted to the ICU of a university hospital from January 2013 to October 2018. Results were evaluated via descriptive analysis. The Log–Rank test was used to analyze the hospital/ICU length of stay (LOS). RESULTS: The male: female ratio was 2.63:1. Mean age was 53.41 ± 16.57 years (range 8–78 years). Concomitant conditions comprised diabetes mellitus in 10 patients (34.48%), and hypertension in six (20.69%). The main reason for ICU admission was surgical (44.83%). The mean Acute Physiology, Age, Chronic Health Evaluation II (APACHE II) and the Sequential Organ Failure Assessment (SOFA) scores were 13.52 ± 3.18 and 3.83 ± 2.89, respectively. Twenty-eight patients (96.55%) received respiratory support. Sixteen patients (55.17%) had positive bacterial culture results. Fourteen bacterial strains were detected, most of which were gram-positive (72.72%). Mean LOS was 6.89 ± 14.39 days (range 0.5–73 days), and 24.79 ± 16 days in the hospital. The ICU mortality rate was 10.34%. Compared with LA patients without descending necrotizing mediastinitis (DNM), those with DNM had longer ICU and hospital LOS. The laboratory investigations were higher. CONCLUSION: LA patients in ICU were predominantly male, with a wide range age, high incidence of complications, long hospital LOS. Association for Dental Sciences of the Republic of China 2020-12 2020-01-10 /pmc/articles/PMC7816034/ /pubmed/33505615 http://dx.doi.org/10.1016/j.jds.2019.10.004 Text en © 2020 Association for Dental Sciences of the Republic of China. Publishing services by Elsevier B.V. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Original Article Lin, Qing-Ling Du, Hong-Liang Xiong, Huai-Yu Li, Bin Liu, Jian Xing, Xiao-Hua Characteristics and outcomes of Ludwig's angina in patients admitted to the intensive care unit: A 6-year retrospective study of 29 patients |
title | Characteristics and outcomes of Ludwig's angina in patients admitted to the intensive care unit: A 6-year retrospective study of 29 patients |
title_full | Characteristics and outcomes of Ludwig's angina in patients admitted to the intensive care unit: A 6-year retrospective study of 29 patients |
title_fullStr | Characteristics and outcomes of Ludwig's angina in patients admitted to the intensive care unit: A 6-year retrospective study of 29 patients |
title_full_unstemmed | Characteristics and outcomes of Ludwig's angina in patients admitted to the intensive care unit: A 6-year retrospective study of 29 patients |
title_short | Characteristics and outcomes of Ludwig's angina in patients admitted to the intensive care unit: A 6-year retrospective study of 29 patients |
title_sort | characteristics and outcomes of ludwig's angina in patients admitted to the intensive care unit: a 6-year retrospective study of 29 patients |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7816034/ https://www.ncbi.nlm.nih.gov/pubmed/33505615 http://dx.doi.org/10.1016/j.jds.2019.10.004 |
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