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Ethnic differences in thromboprophylaxis for COVID-19 patients: should they be considered?

Thromboembolic events contribute to morbidity and mortality in coronavirus disease 2019 (COVID-19). As a result, thromboprophylaxis using low-molecular-weight heparin (LMWH) is universally recommended for hospitalized patients based on multiple guidelines. However, ethnic differences with respect to...

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Detalles Bibliográficos
Autores principales: Iba, Toshiaki, Connors, Jean Marie, Spyropoulos, Alex C., Wada, Hideo, Levy, Jerrold H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7816059/
https://www.ncbi.nlm.nih.gov/pubmed/33471294
http://dx.doi.org/10.1007/s12185-021-03078-x
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author Iba, Toshiaki
Connors, Jean Marie
Spyropoulos, Alex C.
Wada, Hideo
Levy, Jerrold H.
author_facet Iba, Toshiaki
Connors, Jean Marie
Spyropoulos, Alex C.
Wada, Hideo
Levy, Jerrold H.
author_sort Iba, Toshiaki
collection PubMed
description Thromboembolic events contribute to morbidity and mortality in coronavirus disease 2019 (COVID-19). As a result, thromboprophylaxis using low-molecular-weight heparin (LMWH) is universally recommended for hospitalized patients based on multiple guidelines. However, ethnic differences with respect to thrombogenicity have been reported and the incidence of thromboembolic events is considered to be lower in the Asian population. Despite the importance of thromboprophylaxis, bleeding is also a side effect that should be considered. We examine the data relating to potential ethnic differences in thrombosis and bleeding in COVID-19. Although sufficient data is not yet available, current evidence does not oppose routine anticoagulant use and thromboprophylaxis using a standard dose of LMWH for admitted patients regardless of ethnicity based on our review.
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spelling pubmed-78160592021-01-21 Ethnic differences in thromboprophylaxis for COVID-19 patients: should they be considered? Iba, Toshiaki Connors, Jean Marie Spyropoulos, Alex C. Wada, Hideo Levy, Jerrold H. Int J Hematol Review Article Thromboembolic events contribute to morbidity and mortality in coronavirus disease 2019 (COVID-19). As a result, thromboprophylaxis using low-molecular-weight heparin (LMWH) is universally recommended for hospitalized patients based on multiple guidelines. However, ethnic differences with respect to thrombogenicity have been reported and the incidence of thromboembolic events is considered to be lower in the Asian population. Despite the importance of thromboprophylaxis, bleeding is also a side effect that should be considered. We examine the data relating to potential ethnic differences in thrombosis and bleeding in COVID-19. Although sufficient data is not yet available, current evidence does not oppose routine anticoagulant use and thromboprophylaxis using a standard dose of LMWH for admitted patients regardless of ethnicity based on our review. Springer Singapore 2021-01-20 2021 /pmc/articles/PMC7816059/ /pubmed/33471294 http://dx.doi.org/10.1007/s12185-021-03078-x Text en © Japanese Society of Hematology 2021 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Review Article
Iba, Toshiaki
Connors, Jean Marie
Spyropoulos, Alex C.
Wada, Hideo
Levy, Jerrold H.
Ethnic differences in thromboprophylaxis for COVID-19 patients: should they be considered?
title Ethnic differences in thromboprophylaxis for COVID-19 patients: should they be considered?
title_full Ethnic differences in thromboprophylaxis for COVID-19 patients: should they be considered?
title_fullStr Ethnic differences in thromboprophylaxis for COVID-19 patients: should they be considered?
title_full_unstemmed Ethnic differences in thromboprophylaxis for COVID-19 patients: should they be considered?
title_short Ethnic differences in thromboprophylaxis for COVID-19 patients: should they be considered?
title_sort ethnic differences in thromboprophylaxis for covid-19 patients: should they be considered?
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7816059/
https://www.ncbi.nlm.nih.gov/pubmed/33471294
http://dx.doi.org/10.1007/s12185-021-03078-x
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