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Genetic and pharmacological inhibition of two‐pore domain potassium channel TREK‐1 alters depression‐related behaviors and neuronal plasticity in the hippocampus in mice

INTRODUCTION: The two‐pore domain potassium channel TREK‐1 is a member of background K(+) channels that are thought to provide baseline regulation of membrane excitability. Recent studies have highlighted the putative role of TREK‐1 in the action of antidepressants, and its antagonists might be pote...

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Detalles Bibliográficos
Autores principales:	Wu, Fangfang, Sun, Hongbin, Gong, Weigang, Li, Xiaoli, Pan, Zhaohui, Shan, Han, Zhang, Zhijun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7816204/ https://www.ncbi.nlm.nih.gov/pubmed/32864894 http://dx.doi.org/10.1111/cns.13450

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