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From SAR Diagnostics to Compound Design: Development Chronology of the Compound Optimization Monitor (COMO) Method
In medicinal chemistry, compound optimization largely depends on chemical knowledge, experience, and intuition, and progress in hit‐to‐lead and lead optimization projects is difficult to estimate. Accordingly, approaches are sought after that aid in assessing the odds of success with an optimization...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7816267/ https://www.ncbi.nlm.nih.gov/pubmed/32282989 http://dx.doi.org/10.1002/minf.202000046 |