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The mutation of BCOR is highly recurrent and oncogenic in mature T-cell lymphoma

BACKGROUND: BCOR acts as a corepressor of BCL6, a potent oncogenic protein in cancers of the lymphoid lineage. We have found the recurrent somatic mutation of BCOR occurred in mature T-cell lymphoma (TCL). The role of BCOR mutation in lymphoid malignancies is unknown. METHODS: Lymphoma patient sampl...

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Detalles Bibliográficos
Autores principales:	Kang, Jin Hyun, Lee, Seung Ho, Lee, Jawon, Choi, Murim, Cho, Junhun, Kim, Seok Jin, Kim, Won Seog, Ko, Young Hyeh, Yoo, Hae Yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7816311/ https://www.ncbi.nlm.nih.gov/pubmed/33468080 http://dx.doi.org/10.1186/s12885-021-07806-8

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