Exercise‐induced ventricular tachycardia in a case with hypertrophic cardiomyopathy taking cibenzoline

We report a 17‐year‐old woman with hypertrophic cardiomyopathy (HCM) successfully resuscitated from ventricular fibrillation while taking cibenzoline. During exercise–stress testing before implanting an implantable cardioverter–defibrillator, ventricular tachycardia was induced and thought to be a p...

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Detalles Bibliográficos
Autores principales: Shiohira, Shinya, Kawabata, Mihoko, Goya, Masahiko, Maeda, Shingo, Sasano, Tetsuo, Hirao, Kenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7816811/
https://www.ncbi.nlm.nih.gov/pubmed/32813916
http://dx.doi.org/10.1111/anec.12789
Descripción
Sumario:We report a 17‐year‐old woman with hypertrophic cardiomyopathy (HCM) successfully resuscitated from ventricular fibrillation while taking cibenzoline. During exercise–stress testing before implanting an implantable cardioverter–defibrillator, ventricular tachycardia was induced and thought to be a proarrhythmia due to the use‐dependent effect of the Na channel blockade with cibenzoline. In patients with arrhythmogenic substrates such as HCM, it is critical to pay attention to the proarrhythmic effects of class I antiarrhythmic drugs while increasing heart rate.

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