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Epitope-resolved profiling of the SARS-CoV-2 antibody response identifies cross-reactivity with endemic human coronaviruses
The SARS-CoV-2 proteome shares regions of conservation with endemic human coronaviruses (CoVs), but it remains unknown to what extent these may be cross-recognized by the antibody response. Here, we study cross-reactivity using a highly multiplexed peptide assay (PepSeq) to generate an epitope-resol...
Autores principales: | Ladner, Jason T., Henson, Sierra N., Boyle, Annalee S., Engelbrektson, Anna L., Fink, Zane W., Rahee, Fatima, D’ambrozio, Jonathan, Schaecher, Kurt E., Stone, Mars, Dong, Wenjuan, Dadwal, Sanjeet, Yu, Jianhua, Caligiuri, Michael A., Cieplak, Piotr, Bjørås, Magnar, Fenstad, Mona H., Nordbø, Svein A., Kainov, Denis E., Muranaka, Norihito, Chee, Mark S., Shiryaev, Sergey A., Altin, John A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7816965/ https://www.ncbi.nlm.nih.gov/pubmed/33495758 http://dx.doi.org/10.1016/j.xcrm.2020.100189 |
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