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Epitope-resolved profiling of the SARS-CoV-2 antibody response identifies cross-reactivity with endemic human coronaviruses

The SARS-CoV-2 proteome shares regions of conservation with endemic human coronaviruses (CoVs), but it remains unknown to what extent these may be cross-recognized by the antibody response. Here, we study cross-reactivity using a highly multiplexed peptide assay (PepSeq) to generate an epitope-resol...

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Detalles Bibliográficos
Autores principales: Ladner, Jason T., Henson, Sierra N., Boyle, Annalee S., Engelbrektson, Anna L., Fink, Zane W., Rahee, Fatima, D’ambrozio, Jonathan, Schaecher, Kurt E., Stone, Mars, Dong, Wenjuan, Dadwal, Sanjeet, Yu, Jianhua, Caligiuri, Michael A., Cieplak, Piotr, Bjørås, Magnar, Fenstad, Mona H., Nordbø, Svein A., Kainov, Denis E., Muranaka, Norihito, Chee, Mark S., Shiryaev, Sergey A., Altin, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7816965/
https://www.ncbi.nlm.nih.gov/pubmed/33495758
http://dx.doi.org/10.1016/j.xcrm.2020.100189

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