Kaposi’s sarcoma-associated herpesvirus latency-associated nuclear antigen dysregulates expression of MCL-1 by targeting FBW7

Primary effusion lymphoma (PEL) is an aggressive B cell lymphoma that is etiologically linked to Kaposi’s sarcoma-associated herpesvirus (KSHV). Despite standard multi-chemotherapy treatment, PEL continues to cause high mortality. Thus, new strategies to control PEL are needed urgently. Here, we sho...

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Detalles Bibliográficos
Autores principales: Kim, Yeong Jun, Kim, Yuri, Kumar, Abhishek, Kim, Chan Woo, Toth, Zsolt, Cho, Nam Hyuk, Lee, Hye-Ra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7816990/
https://www.ncbi.nlm.nih.gov/pubmed/33471866
http://dx.doi.org/10.1371/journal.ppat.1009179

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