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Network propagation of rare variants in Alzheimer’s disease reveals tissue-specific hub genes and communities
State-of-the-art rare variant association testing methods aggregate the contribution of rare variants in biologically relevant genomic regions to boost statistical power. However, testing single genes separately does not consider the complex interaction landscape of genes, nor the downstream effects...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817020/ https://www.ncbi.nlm.nih.gov/pubmed/33411734 http://dx.doi.org/10.1371/journal.pcbi.1008517 |