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In vivo antagonistic role of the Human T-Cell Leukemia Virus Type 1 regulatory proteins Tax and HBZ

Adult T cell leukemia (ATL) is an aggressive malignancy secondary to chronic infection by the human T-cell leukemia virus type 1 (HTLV-1) infection. Two viral proteins, Tax and HBZ, play central roles in ATL leukemogenesis. Tax expression transforms T cells in vitro and induces ATL-like disease in m...

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Detalles Bibliográficos
Autores principales:	Akkouche, Abdou, Moodad, Sara, Hleihel, Rita, Skayneh, Hala, Chambeyron, Séverine, El Hajj, Hiba, Bazarbachi, Ali
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817025/ https://www.ncbi.nlm.nih.gov/pubmed/33471856 http://dx.doi.org/10.1371/journal.ppat.1009219

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