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Epidemiological, socio-demographic and clinical features of the early phase of the COVID-19 epidemic in Ecuador

The SARS-CoV-2 virus has spread rapidly around the globe. Nevertheless, there is limited information describing the characteristics and outcomes of COVID-19 patients in Latin America. We conducted a cross-sectional analysis of 9,468 confirmed COVID-19 cases reported in Ecuador. We calculated overall...

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Autores principales: Ortiz-Prado, Esteban, Simbaña-Rivera, Katherine, Barreno, Lenin Gómez, Diaz, Ana Maria, Barreto, Alejandra, Moyano, Carla, Arcos, Vannesa, Vásconez-González, Eduardo, Paz, Clara, Simbaña-Guaycha, Fernanda, Molestina-Luzuriaga, Martin, Fernández-Naranjo, Raúl, Feijoo, Javier, Henriquez-Trujillo, Aquiles R., Adana, Lila, López-Cortés, Andrés, Fletcher, Isabel, Lowe, Rachel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817051/
https://www.ncbi.nlm.nih.gov/pubmed/33395425
http://dx.doi.org/10.1371/journal.pntd.0008958
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author Ortiz-Prado, Esteban
Simbaña-Rivera, Katherine
Barreno, Lenin Gómez
Diaz, Ana Maria
Barreto, Alejandra
Moyano, Carla
Arcos, Vannesa
Vásconez-González, Eduardo
Paz, Clara
Simbaña-Guaycha, Fernanda
Molestina-Luzuriaga, Martin
Fernández-Naranjo, Raúl
Feijoo, Javier
Henriquez-Trujillo, Aquiles R.
Adana, Lila
López-Cortés, Andrés
Fletcher, Isabel
Lowe, Rachel
author_facet Ortiz-Prado, Esteban
Simbaña-Rivera, Katherine
Barreno, Lenin Gómez
Diaz, Ana Maria
Barreto, Alejandra
Moyano, Carla
Arcos, Vannesa
Vásconez-González, Eduardo
Paz, Clara
Simbaña-Guaycha, Fernanda
Molestina-Luzuriaga, Martin
Fernández-Naranjo, Raúl
Feijoo, Javier
Henriquez-Trujillo, Aquiles R.
Adana, Lila
López-Cortés, Andrés
Fletcher, Isabel
Lowe, Rachel
author_sort Ortiz-Prado, Esteban
collection PubMed
description The SARS-CoV-2 virus has spread rapidly around the globe. Nevertheless, there is limited information describing the characteristics and outcomes of COVID-19 patients in Latin America. We conducted a cross-sectional analysis of 9,468 confirmed COVID-19 cases reported in Ecuador. We calculated overall incidence, mortality, case fatality rates, disability adjusted life years, attack and crude mortality rates, as well as relative risk and relative odds of death, adjusted for age, sex and presence of comorbidities. A total of 9,468 positive COVID-19 cases and 474 deaths were included in the analysis. Men accounted for 55.4% (n = 5, 247) of cases and women for 44.6% (n = 4, 221). We found the presence of comorbidities, being male and older than 65 years were important determinants of mortality. Coastal regions were most affected by COVID-19, with higher mortality rates than the highlands. Fatigue was reported in 53.2% of the patients, followed by headache (43%), dry cough (41.7%), ageusia (37.1%) and anosmia (36.1%). We present an analysis of the burden of COVID-19 in Ecuador. Our findings show that men are at higher risk of dying from COVID-19 than women, and risk increases with age and the presence of comorbidities. We also found that blue-collar workers and the unemployed are at greater risk of dying. These early observations offer clinical insights for the medical community to help improve patient care and for public health officials to strengthen Ecuador’s response to the outbreak.
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spelling pubmed-78170512021-01-28 Epidemiological, socio-demographic and clinical features of the early phase of the COVID-19 epidemic in Ecuador Ortiz-Prado, Esteban Simbaña-Rivera, Katherine Barreno, Lenin Gómez Diaz, Ana Maria Barreto, Alejandra Moyano, Carla Arcos, Vannesa Vásconez-González, Eduardo Paz, Clara Simbaña-Guaycha, Fernanda Molestina-Luzuriaga, Martin Fernández-Naranjo, Raúl Feijoo, Javier Henriquez-Trujillo, Aquiles R. Adana, Lila López-Cortés, Andrés Fletcher, Isabel Lowe, Rachel PLoS Negl Trop Dis Research Article The SARS-CoV-2 virus has spread rapidly around the globe. Nevertheless, there is limited information describing the characteristics and outcomes of COVID-19 patients in Latin America. We conducted a cross-sectional analysis of 9,468 confirmed COVID-19 cases reported in Ecuador. We calculated overall incidence, mortality, case fatality rates, disability adjusted life years, attack and crude mortality rates, as well as relative risk and relative odds of death, adjusted for age, sex and presence of comorbidities. A total of 9,468 positive COVID-19 cases and 474 deaths were included in the analysis. Men accounted for 55.4% (n = 5, 247) of cases and women for 44.6% (n = 4, 221). We found the presence of comorbidities, being male and older than 65 years were important determinants of mortality. Coastal regions were most affected by COVID-19, with higher mortality rates than the highlands. Fatigue was reported in 53.2% of the patients, followed by headache (43%), dry cough (41.7%), ageusia (37.1%) and anosmia (36.1%). We present an analysis of the burden of COVID-19 in Ecuador. Our findings show that men are at higher risk of dying from COVID-19 than women, and risk increases with age and the presence of comorbidities. We also found that blue-collar workers and the unemployed are at greater risk of dying. These early observations offer clinical insights for the medical community to help improve patient care and for public health officials to strengthen Ecuador’s response to the outbreak. Public Library of Science 2021-01-04 /pmc/articles/PMC7817051/ /pubmed/33395425 http://dx.doi.org/10.1371/journal.pntd.0008958 Text en © 2021 Ortiz-Prado et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Ortiz-Prado, Esteban
Simbaña-Rivera, Katherine
Barreno, Lenin Gómez
Diaz, Ana Maria
Barreto, Alejandra
Moyano, Carla
Arcos, Vannesa
Vásconez-González, Eduardo
Paz, Clara
Simbaña-Guaycha, Fernanda
Molestina-Luzuriaga, Martin
Fernández-Naranjo, Raúl
Feijoo, Javier
Henriquez-Trujillo, Aquiles R.
Adana, Lila
López-Cortés, Andrés
Fletcher, Isabel
Lowe, Rachel
Epidemiological, socio-demographic and clinical features of the early phase of the COVID-19 epidemic in Ecuador
title Epidemiological, socio-demographic and clinical features of the early phase of the COVID-19 epidemic in Ecuador
title_full Epidemiological, socio-demographic and clinical features of the early phase of the COVID-19 epidemic in Ecuador
title_fullStr Epidemiological, socio-demographic and clinical features of the early phase of the COVID-19 epidemic in Ecuador
title_full_unstemmed Epidemiological, socio-demographic and clinical features of the early phase of the COVID-19 epidemic in Ecuador
title_short Epidemiological, socio-demographic and clinical features of the early phase of the COVID-19 epidemic in Ecuador
title_sort epidemiological, socio-demographic and clinical features of the early phase of the covid-19 epidemic in ecuador
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817051/
https://www.ncbi.nlm.nih.gov/pubmed/33395425
http://dx.doi.org/10.1371/journal.pntd.0008958
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