Kinesin-4 KIF21B limits microtubule growth to allow rapid centrosome polarization in T cells

When a T cell and an antigen-presenting cell form an immunological synapse, rapid dynein-driven translocation of the centrosome toward the contact site leads to reorganization of microtubules and associated organelles. Currently, little is known about how the regulation of microtubule dynamics contr...

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Detalles Bibliográficos
Autores principales: Hooikaas, Peter Jan, Damstra, Hugo GJ, Gros, Oane J, van Riel, Wilhelmina E, Martin, Maud, Smits, Yesper TH, van Loosdregt, Jorg, Kapitein, Lukas C, Berger, Florian, Akhmanova, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817182/
https://www.ncbi.nlm.nih.gov/pubmed/33346730
http://dx.doi.org/10.7554/eLife.62876

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817182/
https://www.ncbi.nlm.nih.gov/pubmed/33346730
http://dx.doi.org/10.7554/eLife.62876

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