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Preliminary Study on the Application of Ultrahigh Field Magnetic Resonance in Moyamoya Disease

Magnetic resonance imaging (MRI) is widely used for the evaluation of moyamoya disease (MMD). In this paper, we describe the features of time-of-flight magnetic resonance angiography (TOF-MRA) and susceptibility-weighted imaging (SWI) at 7 T in a series of MMD patients. In this prospective pilot stu...

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Autores principales: Su, Jiabin, Ni, Wei, Yang, Baofeng, Xiao, Weiping, Gao, Xinjie, Yang, Heng, Li, Yanjiang, Lei, Yu, Jiang, Hanqiang, Wang, He, Gu, Yuxiang, Mao, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817260/
https://www.ncbi.nlm.nih.gov/pubmed/33520085
http://dx.doi.org/10.1155/2021/5653948
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author Su, Jiabin
Ni, Wei
Yang, Baofeng
Xiao, Weiping
Gao, Xinjie
Yang, Heng
Li, Yanjiang
Lei, Yu
Jiang, Hanqiang
Wang, He
Gu, Yuxiang
Mao, Ying
author_facet Su, Jiabin
Ni, Wei
Yang, Baofeng
Xiao, Weiping
Gao, Xinjie
Yang, Heng
Li, Yanjiang
Lei, Yu
Jiang, Hanqiang
Wang, He
Gu, Yuxiang
Mao, Ying
author_sort Su, Jiabin
collection PubMed
description Magnetic resonance imaging (MRI) is widely used for the evaluation of moyamoya disease (MMD). In this paper, we describe the features of time-of-flight magnetic resonance angiography (TOF-MRA) and susceptibility-weighted imaging (SWI) at 7 T in a series of MMD patients. In this prospective pilot study, 7 patients (median age: 45.6 years; range: 30-52 years) with MMD and no contraindications for MRI underwent T2-weighted, SWI, and TOF-MRA sequences using a research 7 T head-only scanner. We show that such sequences at ultrahigh field (UHF) represent new and valuable approaches to unravel and characterize MMD. While SWI reveals more remarkable imaging signs related to an improved magnitude and phase contrast imaging, the collateral network pathways in MMD could be excellently delineated using 7 T TOF-MRA. In particular, using SWI and MRA fusion images in UHF MRI helps to improve the detection of bleeding points in hemorrhagic MMD. Our findings indicate that ultrahigh field MRI is very promising to access the severity of the disease and may facilitate revascularization surgery of MMD patients.
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spelling pubmed-78172602021-01-28 Preliminary Study on the Application of Ultrahigh Field Magnetic Resonance in Moyamoya Disease Su, Jiabin Ni, Wei Yang, Baofeng Xiao, Weiping Gao, Xinjie Yang, Heng Li, Yanjiang Lei, Yu Jiang, Hanqiang Wang, He Gu, Yuxiang Mao, Ying Oxid Med Cell Longev Research Article Magnetic resonance imaging (MRI) is widely used for the evaluation of moyamoya disease (MMD). In this paper, we describe the features of time-of-flight magnetic resonance angiography (TOF-MRA) and susceptibility-weighted imaging (SWI) at 7 T in a series of MMD patients. In this prospective pilot study, 7 patients (median age: 45.6 years; range: 30-52 years) with MMD and no contraindications for MRI underwent T2-weighted, SWI, and TOF-MRA sequences using a research 7 T head-only scanner. We show that such sequences at ultrahigh field (UHF) represent new and valuable approaches to unravel and characterize MMD. While SWI reveals more remarkable imaging signs related to an improved magnitude and phase contrast imaging, the collateral network pathways in MMD could be excellently delineated using 7 T TOF-MRA. In particular, using SWI and MRA fusion images in UHF MRI helps to improve the detection of bleeding points in hemorrhagic MMD. Our findings indicate that ultrahigh field MRI is very promising to access the severity of the disease and may facilitate revascularization surgery of MMD patients. Hindawi 2021-01-13 /pmc/articles/PMC7817260/ /pubmed/33520085 http://dx.doi.org/10.1155/2021/5653948 Text en Copyright © 2021 Jiabin Su et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Su, Jiabin
Ni, Wei
Yang, Baofeng
Xiao, Weiping
Gao, Xinjie
Yang, Heng
Li, Yanjiang
Lei, Yu
Jiang, Hanqiang
Wang, He
Gu, Yuxiang
Mao, Ying
Preliminary Study on the Application of Ultrahigh Field Magnetic Resonance in Moyamoya Disease
title Preliminary Study on the Application of Ultrahigh Field Magnetic Resonance in Moyamoya Disease
title_full Preliminary Study on the Application of Ultrahigh Field Magnetic Resonance in Moyamoya Disease
title_fullStr Preliminary Study on the Application of Ultrahigh Field Magnetic Resonance in Moyamoya Disease
title_full_unstemmed Preliminary Study on the Application of Ultrahigh Field Magnetic Resonance in Moyamoya Disease
title_short Preliminary Study on the Application of Ultrahigh Field Magnetic Resonance in Moyamoya Disease
title_sort preliminary study on the application of ultrahigh field magnetic resonance in moyamoya disease
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817260/
https://www.ncbi.nlm.nih.gov/pubmed/33520085
http://dx.doi.org/10.1155/2021/5653948
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