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Utility of Serial Donor-derived Cell-free DNA Measurements for Detecting Allograft Rejection in a Kidney Transplant Recipient After PD-1 Checkpoint Inhibitor Administration

BACKGROUND. Donor-derived cell-free DNA (dd-cfDNA) is a useful biomarker of rejection that originates from allograft cells undergoing injury. Plasma levels <1% in kidney transplant recipients have a high negative predictive value for active allograft rejection. The utility of this biomarker in ki...

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Detalles Bibliográficos
Autores principales:	Lakhani, Laila, Alasfar, Sami, Bhalla, Anshul, Aala, Amtul, Rosenberg, Avi, Ostrander, Darin, Schollenberger, Megan D., Brennan, Daniel C., Lipson, Evan J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2021
Materias:	Kidney Transplantation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817285/ https://www.ncbi.nlm.nih.gov/pubmed/33490381 http://dx.doi.org/10.1097/TXD.0000000000001113

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