Comparative host transcriptome in response to pathogenic fungi identifies common and species-specific transcriptional antifungal host response pathways

Candidiasis, aspergillosis, and mucormycosis cause the majority of nosocomial fungal infections in immunocompromised patients. Using an unbiased transcriptional profiling in PBMCs exposed to the fungal species causing these infections, we found a core host response in healthy individuals that may go...

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Detalles Bibliográficos
Autores principales: Bruno, Mariolina, Dewi, Intan M.W., Matzaraki, Vicky, ter Horst, Rob, Pekmezovic, Marina, Rösler, Berenice, Groh, Laszlo, Röring, Rutger J., Kumar, Vinod, Li, Yang, Carvalho, Agostinho, Netea, Mihai G., Latgé, Jean-Paul, Gresnigt, Mark S., van de Veerdonk, Frank L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817431/
https://www.ncbi.nlm.nih.gov/pubmed/33510868
http://dx.doi.org/10.1016/j.csbj.2020.12.036

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