Cargando…
UPR(mt) scales mitochondrial network expansion with protein synthesis via mitochondrial import in Caenorhabditis elegans
As organisms develop, individual cells generate mitochondria to fulfill physiological requirements. However, it remains unknown how mitochondrial network expansion is scaled to cell growth. The mitochondrial unfolded protein response (UPR(mt)) is a signaling pathway mediated by the transcription fac...
Autores principales: | Shpilka, Tomer, Du, YunGuang, Yang, Qiyuan, Melber, Andrew, Uma Naresh, Nandhitha, Lavelle, Joshua, Kim, Sookyung, Liu, Pengpeng, Weidberg, Hilla, Li, Rui, Yu, Jun, Zhu, Lihua Julie, Strittmatter, Lara, Haynes, Cole M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817664/ https://www.ncbi.nlm.nih.gov/pubmed/33473112 http://dx.doi.org/10.1038/s41467-020-20784-y |
Ejemplares similares
-
Mitochondrial genome recovery by ATFS-1 is essential for development after starvation
por: Naresh, Nandhitha Uma, et al.
Publicado: (2022) -
LONP-1 and ATFS-1 sustain deleterious heteroplasmy by promoting mtDNA
replication in dysfunctional mitochondria
por: Yang, Qiyuan, et al.
Publicado: (2022) -
UPR(mt) regulation and output: a stress response mediated by mitochondrial-nuclear communication
por: Melber, Andrew, et al.
Publicado: (2018) -
Genome-wide RNAi screen for regulators of UPR(mt) in Caenorhabditis elegans mutants with defects in mitochondrial fusion
por: Haeussler, Simon, et al.
Publicado: (2021) -
mtDNA, Metastasis, and the Mitochondrial Unfolded Protein Response (UPR(mt))
por: Kenny, Timothy C., et al.
Publicado: (2017)