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Aberrant development of pancreatic beta cells derived from human iPSCs with FOXA2 deficiency
FOXA2 has been identified as an essential factor for pancreas development and emerging evidence supports an association between FOXA2 and diabetes. Although the role of FOXA2 during pancreatic development is well-studied in animal models, its role during human islet cell development remains unclear....
Autores principales: | Elsayed, Ahmed K., Younis, Ihab, Ali, Gowher, Hussain, Khalid, Abdelalim, Essam M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817686/ https://www.ncbi.nlm.nih.gov/pubmed/33473118 http://dx.doi.org/10.1038/s41419-021-03390-8 |
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