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Loss of G-Protein Pathway Suppressor 2 Promotes Tumor Growth Through Activation of AKT Signaling
G Protein Suppressor 2 (GPS2) is a multifunctional protein that exerts important roles in inflammation and metabolism in adipose, liver, and immune cells. GPS2 has recently been identified as a significantly mutated gene in breast cancer and other malignancies and proposed to work as a putative tumo...
Autores principales: | Chan, Stefanie, Smith, Emma, Gao, Yuan, Kwan, Julian, Blum, Benjamin C., Tilston-Lunel, Andrew M., Turcinovic, Isabella, Varelas, Xaralabos, Cardamone, Maria Dafne, Monti, Stefano, Emili, Andrew, Perissi, Valentina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817781/ https://www.ncbi.nlm.nih.gov/pubmed/33490071 http://dx.doi.org/10.3389/fcell.2020.608044 |
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