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Systematic review of global clinical practice guidelines for neonatal hyperbilirubinemia
OBJECTIVE: Hyperbilirubinemia is one of the most common clinical symptoms in newborns. To improve patient outcomes, evidence-based and implementable guidelines are required. However, clinical guidelines may vary in quality, criteria and recommendations among regions and countries. In this study, we...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817798/ https://www.ncbi.nlm.nih.gov/pubmed/33468526 http://dx.doi.org/10.1136/bmjopen-2020-040182 |
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author | Zhang, Meng Tang, Jun He, Yang Li, Wenxing Chen, Zhong Xiong, Tao Qu, Yi Li, Youping Mu, Dezhi |
author_facet | Zhang, Meng Tang, Jun He, Yang Li, Wenxing Chen, Zhong Xiong, Tao Qu, Yi Li, Youping Mu, Dezhi |
author_sort | Zhang, Meng |
collection | PubMed |
description | OBJECTIVE: Hyperbilirubinemia is one of the most common clinical symptoms in newborns. To improve patient outcomes, evidence-based and implementable guidelines are required. However, clinical guidelines may vary in quality, criteria and recommendations among regions and countries. In this study, we aimed to systematically assess the quality of guidelines using the Appraisal of Guidelines for Research & Evaluation (AGREE)-II instrument and summarise the specific recommendations for neonatal hyperbilirubinemia in order to provide suggestions for future guideline development. DESIGN: Systematic review. INTERVENTIONS: We searched the PubMed, Embase, Medline and guideline databases for relevant articles on 10 April 2020. The studies were screened by two independent reviewers according to our inclusion criteria. Two reviewers independently extracted the descriptive data. Four appraisers assessed the guidelines using the AGREE-II instrument. RESULTS: Our systematic review appraised 12 clinical practice guidelines for the diagnosis and management of neonatal hyperbilirubinemia. The 12 guidelines achieved an average score of 36%–89%. The guidelines received the highest scores for clarity of presentation and lowest scores for rigour of development. Most recommendations for diagnosis were relatively consistent, but recommendations regarding risk factors, the initiating threshold of treatment and pharmacotherapy varied. CONCLUSIONS: Our study revealed that current guidelines vary in the quality of the developing process and are inconsistent with regards to recommendations. Future guidelines should afford more attention to the quality of methodologies in guideline development, and more qualified evidence is needed to standardise the initiating threshold of treatment for neonatal hyperbilirubinemia. |
format | Online Article Text |
id | pubmed-7817798 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-78177982021-01-28 Systematic review of global clinical practice guidelines for neonatal hyperbilirubinemia Zhang, Meng Tang, Jun He, Yang Li, Wenxing Chen, Zhong Xiong, Tao Qu, Yi Li, Youping Mu, Dezhi BMJ Open Paediatrics OBJECTIVE: Hyperbilirubinemia is one of the most common clinical symptoms in newborns. To improve patient outcomes, evidence-based and implementable guidelines are required. However, clinical guidelines may vary in quality, criteria and recommendations among regions and countries. In this study, we aimed to systematically assess the quality of guidelines using the Appraisal of Guidelines for Research & Evaluation (AGREE)-II instrument and summarise the specific recommendations for neonatal hyperbilirubinemia in order to provide suggestions for future guideline development. DESIGN: Systematic review. INTERVENTIONS: We searched the PubMed, Embase, Medline and guideline databases for relevant articles on 10 April 2020. The studies were screened by two independent reviewers according to our inclusion criteria. Two reviewers independently extracted the descriptive data. Four appraisers assessed the guidelines using the AGREE-II instrument. RESULTS: Our systematic review appraised 12 clinical practice guidelines for the diagnosis and management of neonatal hyperbilirubinemia. The 12 guidelines achieved an average score of 36%–89%. The guidelines received the highest scores for clarity of presentation and lowest scores for rigour of development. Most recommendations for diagnosis were relatively consistent, but recommendations regarding risk factors, the initiating threshold of treatment and pharmacotherapy varied. CONCLUSIONS: Our study revealed that current guidelines vary in the quality of the developing process and are inconsistent with regards to recommendations. Future guidelines should afford more attention to the quality of methodologies in guideline development, and more qualified evidence is needed to standardise the initiating threshold of treatment for neonatal hyperbilirubinemia. BMJ Publishing Group 2021-01-18 /pmc/articles/PMC7817798/ /pubmed/33468526 http://dx.doi.org/10.1136/bmjopen-2020-040182 Text en © Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) . |
spellingShingle | Paediatrics Zhang, Meng Tang, Jun He, Yang Li, Wenxing Chen, Zhong Xiong, Tao Qu, Yi Li, Youping Mu, Dezhi Systematic review of global clinical practice guidelines for neonatal hyperbilirubinemia |
title | Systematic review of global clinical practice guidelines for neonatal hyperbilirubinemia |
title_full | Systematic review of global clinical practice guidelines for neonatal hyperbilirubinemia |
title_fullStr | Systematic review of global clinical practice guidelines for neonatal hyperbilirubinemia |
title_full_unstemmed | Systematic review of global clinical practice guidelines for neonatal hyperbilirubinemia |
title_short | Systematic review of global clinical practice guidelines for neonatal hyperbilirubinemia |
title_sort | systematic review of global clinical practice guidelines for neonatal hyperbilirubinemia |
topic | Paediatrics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817798/ https://www.ncbi.nlm.nih.gov/pubmed/33468526 http://dx.doi.org/10.1136/bmjopen-2020-040182 |
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