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Secreted KIAA1199 promotes the progression of rheumatoid arthritis by mediating hyaluronic acid degradation in an ANXA1-dependent manner

In inflamed joints, enhanced hyaluronic acid (HA) degradation is closely related to the pathogenesis of rheumatoid arthritis (RA). KIAA1199 has been identified as a hyaladherin that mediates the intracellular degradation of HA, but its extracellular function remains unclear. In this study, we found...

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Detalles Bibliográficos
Autores principales:	Zhang, Wei, Yin, Guoyu, Zhao, Heping, Ling, Hanzhi, Xie, Zhen, Xiao, Chipeng, Chen, Yan, Lin, Yufan, Jiang, Tao, Jin, Shengwei, Wang, Jianguang, Yang, Xinyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817834/ https://www.ncbi.nlm.nih.gov/pubmed/33473125 http://dx.doi.org/10.1038/s41419-021-03393-5

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