Cargando…

Structure of a microtubule-bound axonemal dynein

Axonemal dyneins are tethered to doublet microtubules inside cilia to drive ciliary beating, a process critical for cellular motility and extracellular fluid flow. Axonemal dyneins are evolutionarily and biochemically distinct from cytoplasmic dyneins that transport cargo, and the mechanisms regulat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Walton, Travis, Wu, Hao, Brown, Alan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817835/ https://www.ncbi.nlm.nih.gov/pubmed/33473120 http://dx.doi.org/10.1038/s41467-020-20735-7

Ejemplares similares

Cryo-EM of dynein microtubule-binding domains shows how an axonemal dynein distorts the microtubule
por: Lacey, Samuel E, et al.
Publicado: (2019)

A microtubule-dynein tethering complex regulates the axonemal inner dynein f (I1)
por: Kubo, Tomohiro, et al.
Publicado: (2018)

Processivity vs. Beating: Comparing Cytoplasmic and Axonemal Dynein Microtubule Binding Domain Association with Microtubule
por: Tajielyato, Nayere, et al.
Publicado: (2019)

Microtubule sliding in mutant Chlamydomonas axonemes devoid of outer or inner dynein arms
Publicado: (1986)

Structural organization of the dynein-dynactin complex bound to microtubules
por: Chowdhury, Saikat, et al.
Publicado: (2015)

Axonemal dynein light chain-1 locates at the microtubule-binding domain of the γ heavy chain
por: Ichikawa, Muneyoshi, et al.
Publicado: (2015)

Regulation of dynein-driven microtubule sliding by the axonemal protein kinase CK1 in Chlamydomonas flagella
por: Gokhale, Avanti, et al.
Publicado: (2009)

Polarity and asymmetry in the arrangement of dynein and related structures in the Chlamydomonas axoneme
por: Bui, Khanh Huy, et al.
Publicado: (2012)

The Motility of Axonemal Dynein Is Regulated by the Tubulin Code
por: Alper, Joshua D., et al.
Publicado: (2014)

Structural and functional reconstitution of inner dynein arms in Chlamydomonas flagellar axonemes
Publicado: (1992)

Regulation of Chlamydomonas flagellar dynein by an axonemal protein kinase
Publicado: (1994)

Force-Generating Mechanism of Axonemal Dynein in Solo and Ensemble
por: Ishibashi, Kenta, et al.
Publicado: (2020)

Axonemal structures reveal mechanoregulatory and disease mechanisms
por: Walton, Travis, et al.
Publicado: (2023)

Effects of antibodies against dynein and tubulin on the stiffness of flagellar axonemes
Publicado: (1981)

Isolation of a sixth dynein subunit adenosine triphosphatase of Chlamydomonas axonemes
Publicado: (1988)

The dynein electrophoretic bands in axonemes naturally lacking the inner or the outer arm
Publicado: (1979)

Ktu/PF13 is required for cytoplasmic pre-assembly of axonemal dyneins
por: Omran, Heymut, et al.
Publicado: (2008)

The CSC connects three major axonemal complexes involved in dynein regulation
por: Heuser, Thomas, et al.
Publicado: (2012)

WDR92 is required for axonemal dynein heavy chain stability in cytoplasm
por: Patel-King, Ramila S., et al.
Publicado: (2019)

Mutations in the "dynein regulatory complex" alter the ATP-insensitive binding sites for inner arm dyneins in Chlamydomonas axonemes
Publicado: (1994)

THE ARRANGEMENT OF THE AXONEMAL MICROTUBULES AND LINKS OF ECHINOSPHAERIUM NUCLEOFILUM
por: Harris, W. F.
Publicado: (1970)

ZMYND10 functions in a chaperone relay during axonemal dynein assembly
por: Mali, Girish R, et al.
Publicado: (2018)

Functional partitioning of a liquid-like organelle during assembly of axonemal dyneins
por: Lee, Chanjae, et al.
Publicado: (2020)

Discrete PIH proteins function in the cytoplasmic preassembly of different subsets of axonemal dyneins
por: Yamamoto, Ryosuke, et al.
Publicado: (2010)

Mechanosignaling between central apparatus and radial spokes controls axonemal dynein activity
por: Oda, Toshiyuki, et al.
Publicado: (2014)

Dynein axonemal intermediate chain 2 plays a role in gametogenesis by activation of Stat3
por: Yang, Zhaojuan, et al.
Publicado: (2018)

Three distinct inner dynein arms in Chlamydomonas flagella: molecular composition and location in the axoneme
Publicado: (1990)

Mutations in axonemal dynein assembly factor DNAAF3 cause primary ciliary dyskinesia
por: Mitchison, Hannah M., et al.
Publicado: (2012)

Diverse Roles of Axonemal Dyneins in Drosophila Auditory Neuron Function and Mechanical Amplification in Hearing
por: Karak, Somdatta, et al.
Publicado: (2015)

Pih1d3 is required for cytoplasmic preassembly of axonemal dynein in mouse sperm
por: Dong, Fenglan, et al.
Publicado: (2014)

Vertebrate Dynein-f depends on Wdr78 for axonemal localization and is essential for ciliary beat
por: Zhang, Yirong, et al.
Publicado: (2018)

Electron cryo-tomography structure of axonemal doublet microtubule from Tetrahymena thermophila
por: Li, Sam, et al.
Publicado: (2021)

NEW OBSERVATIONS ON FLAGELLAR FINE STRUCTURE : The Relationship Between Matrix Structure and the Microtubule Component of the Axoneme
por: Warner, Fred D.
Publicado: (1970)

ATP‐induced conformational change of axonemal outer dynein arms revealed by cryo‐electron tomography
por: Zimmermann, Noemi, et al.
Publicado: (2023)

Microtubule asters anchored by FSD1 control axoneme assembly and ciliogenesis
por: Tu, Hai-Qing, et al.
Publicado: (2018)

Systematic studies of all PIH proteins in zebrafish reveal their distinct roles in axonemal dynein assembly
por: Yamaguchi, Hiroshi, et al.
Publicado: (2018)

She1 affects dynein through direct interactions with the microtubule and the dynein microtubule-binding domain
por: Ecklund, Kari H., et al.
Publicado: (2017)

HOW MICROTUBULE PATTERNS ARE GENERATED : The Relative Importance of Nucleation and Bridging of Microtubules in the Formation of the Axoneme of Raphidiophrys
por: Tilney, Lewis G.
Publicado: (1971)

Chlamydomonas Axonemal Dynein Assembly Locus ODA8 Encodes a Conserved Flagellar Protein Needed for Cytoplasmic Maturation of Outer Dynein Arm Complexes
por: Desai, Paurav B, et al.
Publicado: (2015)

Bending motion of Chlamydomonas axonemes after extrusion of central- pair microtubules
Publicado: (1987)

Cannot write session to /tmp/vufind_sessions/sess_kfjmtq9pmqnp5bnp57keegfrbj