Cargando…

Analysis of Wild Type LbCpf1 Protein, and PAM Recognition Variants, in a Cellular Context

Nucleases used in genome engineering induce hydrolysis of DNA phosphate backbone in a sequence-specific manner. So far CRISPR-Cas, the RNA-guided nucleases, is the most advanced genome engineering system. The CRISPR nucleases allows recognition of a particular genomic sequence with two distinct mole...

Descripción completa

Detalles Bibliográficos
Autores principales: Shin, Ujin, Brondani, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817983/
https://www.ncbi.nlm.nih.gov/pubmed/33488667
http://dx.doi.org/10.3389/fgene.2020.571591