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Analysis of Wild Type LbCpf1 Protein, and PAM Recognition Variants, in a Cellular Context
Nucleases used in genome engineering induce hydrolysis of DNA phosphate backbone in a sequence-specific manner. So far CRISPR-Cas, the RNA-guided nucleases, is the most advanced genome engineering system. The CRISPR nucleases allows recognition of a particular genomic sequence with two distinct mole...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7817983/ https://www.ncbi.nlm.nih.gov/pubmed/33488667 http://dx.doi.org/10.3389/fgene.2020.571591 |