Analysis of CRISPR‐Cas9 screens identifies genetic dependencies in melanoma

Targeting the MAPK signaling pathway has transformed the treatment of metastatic melanoma. CRISPR‐Cas9 genetic screens provide a genome‐wide approach to uncover novel genetic dependencies that might serve as therapeutic targets. Here, we analyzed recently reported CRISPR‐Cas9 screens comparing data...

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Detalles Bibliográficos
Autores principales: Christodoulou, Eirini, Rashid, Mamunur, Pacini, Clare, Droop, Alastair, Robertson, Holly, van Groningen, Tim, Teunisse, Amina F. A. S., Iorio, Francesco, Jochemsen, Aart G., Adams, David J., van Doorn, Remco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7818247/
https://www.ncbi.nlm.nih.gov/pubmed/32767816
http://dx.doi.org/10.1111/pcmr.12919

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