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Genomic and signalling pathway characterization of the NZM panel of melanoma cell lines: A valuable model for studying the impact of genetic diversity in melanoma

Melanoma is a disease associated with a very high mutation burden and thus the possibility of a diverse range of oncogenic mechanisms that allow it to evade therapeutic interventions and the immune system. Here, we describe the characterization of a panel of 102 cell lines from metastatic melanomas...

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Detalles Bibliográficos
Autores principales: Tran, Khanh B., Gimenez, Gregory, Tsai, Peter, Kolekar, Sharada, Rodger, Euan J., Chatterjee, Aniruddha, Jabed, Anower, Shih, Jen‐Hsing, Joseph, Wayne R., Marshall, Elaine S., Wang, Qian, Print, Cristin G., Eccles, Michael R., Baguley, Bruce C., Shepherd, Peter R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7818249/
https://www.ncbi.nlm.nih.gov/pubmed/32567790
http://dx.doi.org/10.1111/pcmr.12908