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A new clustering method identifies multiple sclerosis‐specific T‐cell receptors
OBJECTIVE: To characterize T‐cell receptors (TCRs) and identify target epitopes in multiple sclerosis (MS). METHODS: Peripheral blood mononuclear cells were obtained from 39 MS patients and 19 healthy controls (HCs). TCR repertoires for α/β/δ/γ chains, TCR diversity, and V/J usage were determined by...
Autores principales: | Hayashi, Fumie, Isobe, Noriko, Glanville, Jacob, Matsushita, Takuya, Maimaitijiang, Guzailiayi, Fukumoto, Shoko, Watanabe, Mitsuru, Masaki, Katsuhisa, Kira, Jun‐ichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7818280/ https://www.ncbi.nlm.nih.gov/pubmed/33400858 http://dx.doi.org/10.1002/acn3.51264 |
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