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Idarubicin–Gold Complex: From Crystal Growth to Gold Nanoparticles

[Image: see text] Idarubicin (IDA) is the analog of daunorubicin (DNR). The absence of the methoxy group at position 4 of IDA remarkably improved lipophilicity, which is responsible for extra cellular uptake, higher DNA-binding ability, and considerable cytotoxicity in correlation with doxorubicin (...

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Detalles Bibliográficos
Autores principales: Barbey, Carole, Bouchemal, Nadia, Retailleau, Pascal, Dupont, Nathalie, Spadavecchia, Jolanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7818310/
https://www.ncbi.nlm.nih.gov/pubmed/33490782
http://dx.doi.org/10.1021/acsomega.0c04501