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Analysis of shared common genetic risk between amyotrophic lateral sclerosis and epilepsy
Because hyper-excitability has been shown to be a shared pathophysiological mechanism, we used the latest and largest genome-wide studies in amyotrophic lateral sclerosis (n = 36,052) and epilepsy (n = 38,349) to determine genetic overlap between these conditions. First, we showed no significant gen...
Autores principales: | Schijven, Dick, Stevelink, Remi, McCormack, Mark, van Rheenen, Wouter, Luykx, Jurjen J., Koeleman, Bobby P.C., Veldink, Jan H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7818383/ https://www.ncbi.nlm.nih.gov/pubmed/32409253 http://dx.doi.org/10.1016/j.neurobiolaging.2020.04.011 |
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