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Simultaneous pectus excavatum correction and lung transplantation–A case series

Severe chest wall deformities are considered an absolute contraindication for lung transplantation. The significantly impaired chest compliance associated with pectus excavatum is thought to result in a high risk of postoperative respiratory complications and significant morbidity and mortality. We...

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Autores principales: Rahimi, Nina, Matilla, Jose R., Lang, György, Schwarz, Stefan, Nachbaur, Edith, Benazzo, Alberto, Klepetko, Walter, Jaksch, Peter, Hoetzenecker, Konrad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7818405/
https://www.ncbi.nlm.nih.gov/pubmed/32619074
http://dx.doi.org/10.1111/ajt.16180
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author Rahimi, Nina
Matilla, Jose R.
Lang, György
Schwarz, Stefan
Nachbaur, Edith
Benazzo, Alberto
Klepetko, Walter
Jaksch, Peter
Hoetzenecker, Konrad
author_facet Rahimi, Nina
Matilla, Jose R.
Lang, György
Schwarz, Stefan
Nachbaur, Edith
Benazzo, Alberto
Klepetko, Walter
Jaksch, Peter
Hoetzenecker, Konrad
author_sort Rahimi, Nina
collection PubMed
description Severe chest wall deformities are considered an absolute contraindication for lung transplantation. The significantly impaired chest compliance associated with pectus excavatum is thought to result in a high risk of postoperative respiratory complications and significant morbidity and mortality. We herein report our pooled institutional experience consisting of 3 patients who underwent bilateral lung transplantation and simultaneous correction of a pectus excavatum. Two of the patients were children and 1 patient had severe asymmetric pectus. All patients received a size‐reduced double lung transplant and the deformity was corrected by a Nuss or modified Ravitch procedure. The perioperative course was complicated by prolonged weaning requiring tracheostomy in 2 of the 3 patients. However, long‐term results were good and all 3 patients are alive in excellent clinical condition 72, 60, and 12 months after the transplantation. This case series demonstrates that patients with severe chest wall deformities should not a priori be excluded from lung transplantation, and a combined approach is feasible for selected patients.
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spelling pubmed-78184052021-01-29 Simultaneous pectus excavatum correction and lung transplantation–A case series Rahimi, Nina Matilla, Jose R. Lang, György Schwarz, Stefan Nachbaur, Edith Benazzo, Alberto Klepetko, Walter Jaksch, Peter Hoetzenecker, Konrad Am J Transplant Case Reports Severe chest wall deformities are considered an absolute contraindication for lung transplantation. The significantly impaired chest compliance associated with pectus excavatum is thought to result in a high risk of postoperative respiratory complications and significant morbidity and mortality. We herein report our pooled institutional experience consisting of 3 patients who underwent bilateral lung transplantation and simultaneous correction of a pectus excavatum. Two of the patients were children and 1 patient had severe asymmetric pectus. All patients received a size‐reduced double lung transplant and the deformity was corrected by a Nuss or modified Ravitch procedure. The perioperative course was complicated by prolonged weaning requiring tracheostomy in 2 of the 3 patients. However, long‐term results were good and all 3 patients are alive in excellent clinical condition 72, 60, and 12 months after the transplantation. This case series demonstrates that patients with severe chest wall deformities should not a priori be excluded from lung transplantation, and a combined approach is feasible for selected patients. John Wiley and Sons Inc. 2020-08-04 2021-01 /pmc/articles/PMC7818405/ /pubmed/32619074 http://dx.doi.org/10.1111/ajt.16180 Text en © 2020 The Authors. American Journal of Transplantation published by Wiley Periodicals LLC on behalf of The American Society of Transplantation and the American Society of Transplant Surgeons This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Case Reports
Rahimi, Nina
Matilla, Jose R.
Lang, György
Schwarz, Stefan
Nachbaur, Edith
Benazzo, Alberto
Klepetko, Walter
Jaksch, Peter
Hoetzenecker, Konrad
Simultaneous pectus excavatum correction and lung transplantation–A case series
title Simultaneous pectus excavatum correction and lung transplantation–A case series
title_full Simultaneous pectus excavatum correction and lung transplantation–A case series
title_fullStr Simultaneous pectus excavatum correction and lung transplantation–A case series
title_full_unstemmed Simultaneous pectus excavatum correction and lung transplantation–A case series
title_short Simultaneous pectus excavatum correction and lung transplantation–A case series
title_sort simultaneous pectus excavatum correction and lung transplantation–a case series
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7818405/
https://www.ncbi.nlm.nih.gov/pubmed/32619074
http://dx.doi.org/10.1111/ajt.16180
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