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Allosteric Molecular Switches in Metabotropic Glutamate Receptors

Metabotropic glutamate receptors (mGlu) are class C G protein‐coupled receptors of eight subtypes that are omnipresently expressed in the central nervous system. mGlus have relevance in several psychiatric and neurological disorders, therefore they raise considerable interest as drug targets. Allost...

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Detalles Bibliográficos
Autores principales: Orgován, Zoltán, Ferenczy, György G., Keserű, György M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7818470/
https://www.ncbi.nlm.nih.gov/pubmed/32686363
http://dx.doi.org/10.1002/cmdc.202000444

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